Virion glycoproteins such as glycoprotein D gD are believed to be the dominant antigens of herpes simplex virus 2 HSV This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability: All relevant data are within the paper and its Supporting Information files. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Hence, it is widely agreed that an effective HSV-2 vaccine is an important and unmet medical need. Glycoprotein subunit vaccines represent the most widely studied approach to develop a safe and effective HSV-2 vaccine. Although whole HSV-2 vaccines appear to be more effective than glycoprotein subunit vaccines, we lack a cohesive explanation as to why this should be the case.
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H ow should the criminal law respond to those who pass on sexually transmitted infections STIs? The answer to this question has become more pressing in light of the conviction of David Golding , who pleaded guilty at Northampton crown court to causing grievous bodily harm by passing on genital herpes to his former partner, Cara Lee. In the case of Mohammed Dica in , the court of appeal held that for a person to be liable for recklessly causing serious bodily harm by passing on the virus he must have known his HIV positive status at the relevant time.
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I’m sure my boyfriend doesn’t have herpes, a patient recently told Dr. Lydia Shrier, an adolescent medicine specialist at Children’s Hospital Boston. How could she be so sure? Shrier asked. Because, the patient replied, she had scoped out his body and “there’s nothing irregular about him.
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